Parkinson's constipation miralax. The pediatrician decided it must have been due to constipation, and initially prescribed what he called a “cleaning out” regimen — three adult doses of MiraLAX each day for three days — followed by one dose every day. Parkinson's constipation miralax

 
The pediatrician decided it must have been due to constipation, and initially prescribed what he called a “cleaning out” regimen — three adult doses of MiraLAX each day for three days — followed by one dose every dayParkinson's constipation miralax Some people claim that consuming baking soda helps ease constipation by pulling water into your digestive tract and promoting muscle contractions

Constipation is common in older adults and accounts for about 2. If I don't do either Teff or Yakult, the constipation comes back. 1. Objective: Aim of our study is to evaluate the prevalence of. At a glance. But this rating doesn't mean much because most (~90%) of the reviewers took Miralax for other conditions, for example, constipation or IBS. In an opinion (PDF) issued on August. Constipation is a commonly experienced side effect during cancer treatment and may occur due to various reasons, one of which is the chemotherapy itself. Those of us who live with a chronic illness, such as Parkinson’s disease (PD), know from experience that having a sluggish bowel can be one, if not the MOST devastating,. Scientists point to two explanations for these difficulties. Fiber by Diet: Increase daily intake of raw vegetables and fruits. Gently tap or shake the cap in order to level out the powder and make sure it’s at the 17-gram line. Parkinson’s disease. Osmotic laxatives, like MiraLAX, make stools soft by keeping water in the colon, while stimulant laxatives cause the intestine walls to contract which leads. He was taking a 25/100 pill 4x a day. ”. gas and bloating. Lack of exercise. If Miralax doesn’t work after a week or so, contact your healthcare provider. Stress. Lack of fiber. Check Price. 10. Metamucil is used to help you have regular bowel movements if you have occasional constipation and you can use it every day. It is one of the problems associated with PD. Polyethylene glycol 3350 ( Miralax) is the most commonly used osmotic laxative. 00 - other international versions of ICD-10 K59. You’ll learn all about magnesium, the form to use to help with constipation, and the products we recommend. 29. If Miralax doesn’t work after a week or so, contact your healthcare provider. Eating a diet filled with low-fiber starchy foods, high-fat meat, dairy products and processed, fried, high-fat foods can be a recipe for constipation. Some nonprescription products carry labels warning against use if the patient has problems in swallowing food. Eating large amounts of dairy products. Constipation is a direct symptom of Parkinson’s because of damage that is caused to the nerves that line the gut. Disease-related morbidity and even mortality have been reported in the affected frail elderly. Laxatives typically work within 3 days. "Stimulant" laxatives, such as. Product Website (Available OTC) MiraLax Savings. diarrhea. Constipation is a frequent and known side effect of clozapine, but serious and fatal events continue to be reported. ), exercise regularly at a slow, steady pace, as directed by md if you are able. Start by taking 2 tablets at bedtime, if you do not have a comfortable bowel movement (BM) the next day, take 4 tablets the next night. diarrhea. Symptoms. * See the “ MiraLAX: How to take ” section below for information on preparing the liquid solution. blood in your stools; or. Saline enema (Fleet Enema)The Best Laxatives For Constipation. For many people, it just works. She has been using it for four years now and very rarely complains anymore (if at all). 415-379-5530 Fax: 415-750-6662 Constipation in Parkinson’s Disease Constipation is an almost universal problem among patients with Parksinson’s Disease. Time. sensation of incomplete evacuations for at least 25% of bowel. Oatmeal. neurologic disorders such as Parkinson's disease, multiple sclerosis, or spinal cord injury;Constipation and Urologic Problems In order to understand constipation, one must first understand normal bowel function. Natural Laxative Tablets. cardiac arrest. The more common side effects of Amitiza can include: headache. A medical professional can teach you to do abdominal massage. I blend until smooth and eat 1/4 cup ever morning with a banana. This can help when the impaction is not as close to the anus. ; Enema: Fluid is delivered into the rectum to flush out hardened stool. Two 32-ounce bottles of Gatorade®. One 8. One 8. , Miralax) are tolerated best. The emergency vet I went to also mentioned that too much fiber can cause more constipation, but he said that for an 10-11 pound cat, 1 teaspoon of pumpkin daily should be okay. Sensation of anorectal obstruction/blockage for ≥25% of defecations. This is important to do because it can interact with other drugs, sometimes dangerously. These have a major impact on quality of life and dignity. Incorrect treatment of constipation in PD patients can result in colonic volvulus and pseudo intestinal obstruction, as well as a reduction in the therapeutic effect of anti-PD drugs due to absorption issues. abdominal bloating, cramping, or pain. For colonoscopy prep, the super high dose works great. Broccoli. She was finally diagnosed with a chronic constipation problem and put on Miralax. Miralax is used as a laxative to treat irregular bowel movements or constipation. peripheral nervous systems such as autism, dementia, depression, schizophrenia, multiple sclerosis, Alzheimer’s and Parkinson’s diseases, and similar others [3]. Medically Reviewed Consuming more fruits and vegetables, as well as plenty of water, can help prevent constipation in people with Parkinson's disease. Polyethylene glycol (Miralax): 17 g once daily; this is the best studied osmotic laxative and is most effective for chronic constipation, with slight improvement in stool frequency in IBS-C 7, 8, 51Rectal suppositories. Usual Pediatric Dose for Bowel Preparation: Occasional constipation: Children greater than 6 months of age: 0. It’s great that you have an appointment with a good GI doctor. 16 capfuls of Miralax powder in 64 ounces of liquid . Recommended dose per day is 400 mg. The microbiome is the community of bacteria, viruses, and fungi that live in the digestive system. Miralax, a polyethylene glycol laxative, is available over-the-counter and in generic form. It may involve medications, laxatives, and lifestyle changes. Many different hormones help to regulate the bowels. Common interactions include anxiety among females, and depression among males. Do not use aloe to treat constipation for more than 1 week. Polyethylene glycol (Miralax) is preferred over lactulose for the treatment of constipation because it is more effective and has fewer adverse effects. Increase your fiber intake. The recommended maximum dosage is 17 g taken once per day for 7 days. Some non-motor symptoms may improve with an adjustment to your Parkinson's medication. confusion. g. 8 glasses of water daily) eating a diet high in fiber, and avoiding foods with sugars (pasta, pastries, cheese, rice, etc. Clozapine affects how the intestines (bowels) function in the majority of patients. It may involve medications, laxatives, and lifestyle changes. MiraLAX: MiraLAX is one of the best immediate laxative solutions which provides effective relief against constipation and is well-known for stimulating bowel movements. Note – it may take polyethylene glycol 3350 up to 4 days to work. Pediatric Gastroenterology . It is available in a lower-cost generic form. 5% in patients with Parkinson’s disease . (NOT RED). I’m taking CALM & a probiotic everyday as well as atleast one dose of miralax and still nothing. The dietary adjustments associated with the keto diet can sometimes cause mild constipation. This medicine is in a class of drugs called osmotic laxatives. Dulcolax contains bisacodyl, a stimulant laxative. Summary. It is an osmotic laxative that typically takes one to three days to experience relief from constipation symptoms after taking Miralax, and it is recommended as an effective long-term solution for occasional constipation relief. Constipation is common and can be caused by a lack of liquid in the GI tract, a diet insufficient in fiber or, on rare occasions, issues with the muscles of the colon or pelvis, says Dr. Infrequent passage of stool- fewer than three bowel movements per week. It is generally safe for patients with chronic kidney disease . Summary. Dulcolax tablets generally produce a bowel movement in 6 to 12 hours. The softer the stool, the more easily it can be evacuated. Lifestyle changes or simple OTC options like Miralax, Ex-Lax, or Ducolax usually work at least as well and cost. Summary. antacid medications. Saline enema (Fleet Enema)Psyllium supplements may help improve constipation, cholesterol levels, IBS symptoms, and blood sugar control in people with diabetes. For Constipation "My daughter has been taking Miralax since she was 5. Most times, mild side effects of a drug go away within a few days or a couple of weeks. Sometimes I take a dose once a day for 5 days and have no result at all. "Stimulant" laxatives, such as bisacodyl (Dulcolax) or senna (Senokot), promote muscle contractions in the digestive tract. Taking a constipation-inducing medication may lead to the failure of MiraLax to produce bowel movements. “Drinking lots of water, especially warm or hot water in the morning, can help you have a bowel movement,” encourages Dr. Metamucil is used to help you have regular bowel movements if you have occasional constipation and you can use it every day. Stool Softeners. We have found Miralax to be very helpful for women that have chronic. A. Search the Healthwise Knowledgebase . shes a picky eater but does eat all fruits (including 8-10 prunes daily) except bananas, limit dairy, lots of water and count all sugar/fat intake. All the articles describing gut microbiota of functional constipation and chronic constipation were included (Supplemental Figure 1). osmotic laxatives. adults and children 17 years of age and older: use once a day. Introduction. Approximately 30% of the general population experiences problems with constipation during their lifetime, with women and elderly people being most affected []. You may start taking MiraLAX at the. Regular physical activity can help stimulate your intestines. Domperidone is to be given only by or under the immediate supervision of your doctor. The recommended dosage of MiraLAX for constipation is: Dose: 17 g, which is for dissolving in liquid*. dizziness. By Mayo Clinic Staff. Fecal impaction is a state of prolonged constipation. A tool called an anoscope is used to look inside the anus. gut bugs) that aid in digestion and intestinal motility. Constipation is a medical condition that causes changes to your stool and your ability to go to the bathroom. Frequent use of “rescue” laxatives usually means the regular regimen should be adjusted. 19 Constipation Myths and Facts. If that doesn’t work, we have over the last ten years handed people this formula, which has been a secret that has… The long list of Parkinson's non-motor symptoms includes constipation, memory and thinking (cognitive) changes, low blood pressure, depression or anxiety, sleep problems and others. Constipation, one of the most common prodromal non-motor symptoms of Parkinson’s disease (PD), usually occurs several years earlier than the onset of motor symptoms. Consuming more fruits and vegetables, as well as plenty of water, can help prevent constipation in people with Parkinson's disease. Warm the water over a low flame. INTRODUCTION. Identifying these signs and symptoms is critical to develop an accurate nursing diagnosis for constipation and design effective nursing care plans to address patient needs. Metrus, MD. Few studies evaluate the difference of prevalence between PD and PS and the cause leading to a severe constipation in this diseases. Medicines used to treat Parkinson’s disease. Fiber supplements can effectively induce bowel movements if a low fiber diet is the cause of your constipation. Miralax (polyethylene glycol 3350) draws water into the intestines and is non-constipating. 1038/s41531-018-0042-8 A considerable body of research has recently emerged around nonmotor symptoms in Parkinson's disease. Nursing interventions: 1. Dulcolax is a laxative that stimulates bowel movements. Sensation of anorectal obstruction/blockage for ≥25% of defecations. 100 – 110 pounds. antacid medications. These products hold water in stool to soften it and increase bowel movements. MiraLax is FDA-approved for the short-term treatment of occasional (irregular) constipation in adults 18 and older. Shah also offered these tips for hospitalists to treat patients with constipation: Maximize one therapeutic regimen at a time. Some medicines used to treat depression. Diagnosis. Various factors can cause constipation, but foods that can contribute to constipation include low fiber foods, eggs, sweeteners, and allergens. stress. e. org Constipation is certainly part of Parkinson's. Symptoms of constipation include: Fewer than three stools a week. Another option that works for some people is diet candies containing the. You should be sure you are eating a fiber-rich diet, drinking adequate fluids, and staying physically active. severe and worsening stomach pain. Sometimes I take a dose once a day for 5 days and have no result at all. Constipation may last from a few days to several weeks. Follow these steps: ①. As a result, it makes the stool softer and easier to pass and increases the number of bowel movements. unusual tiredness or weakness. Tell your doctor if you experience serious side effects of MiraLAX including severe or bloody diarrhea, bleeding from your rectum, blood in your stools, or severe and worsening stomach pain, cramping,. Just add some high-fiber foods into the mix. Unlike some laxatives which stimulate the nerves, MiraLAX is a non stimulant osmotic laxative, working naturally with the water in your body to hydrate, soften, and ease stool through the colon gently. Despite the significant clinical relevance of constipation, unfortunately little knowledge exists on effective treatments. Many of us mistakenly drink milk when our stomachs are burning; however, this causes an increase in acid production to break down the dairy. Straining or pain when passing stools. Certain nerve conditions: Some medical conditions — like multiple sclerosis, Parkinson’s disease, spinal cord injuries, and stroke — can affect the way the nerves around the intestines function. When you move your body, the muscles in your intestines are more active, too. For occasional mild constipation this stuff works great. There’s not a known interaction between Linzess and alcohol. Of the total drug interactions, 214 are moderate, and 1 is minor. Abnormal behavior in the litter box (crying, digging, uncleanliness) Loss of appetite. Parkinson’s disease, dementia linked to. Constipation is the prototype of functional gastrointestinal disorders and one of the most prevalent conditions encountered in daily clinical practice []. As the disease progresses, all of these GI. • Age 1 year and older: o Give Miralax powder with a typical starting dose of ½ capful up to a typical maximum dose up to 1 capful per day . 100% of reviewers reported a positive experience, while 0% reported a negative experience. Treating constipation. I would love to hear the suggestions of others with Parkinson’s that have been successful in treating this symptom. By Patrick McNamara, PhD. These GI issues are always accompanied by other health issues (gas,. and prescription laxatives - natural or otherwise, high fiber diet, etc, etc, etc. Look at the tissue of the anus and the surrounding skin. For chronic use, bulk laxatives (fiber) and polyethylene glycol 3350 (“PEG,” e. There are three types of laxatives that take longer (12 hours to 3 days) to work. Bend forward while you are on the toilet to help move the bowel. Until now! We’ve just published a new blog on all things magnesium. Read honest and unbiased product reviews from our users. 64% of reviewers reported a positive effect, while 24% reported a negative effect. However, this is not as useful with more severe cases of. Domperidone is also used to treat nausea and vomiting caused by other drugs used to treat Parkinson's Disease. In March 2022, the Parkinson’s Community Los Angeles hosted a webinar on common gastrointestinal (GI) issues in Parkinson’s disease (PD) and treatment options with gastroenterologist Dr. Some other common causes of constipation include: eating too much dairy. Included in the adverse events reported are serious kidney, urinary, bowel, blood, skin, and neuropsychiatric symptoms - and at least 3 children's deaths. For occasional mild constipation this stuff works great. It is also gluten-free, sugar-free, and preservative-free, making it a safe choice for a wide range of people. Miralax is in the drug class laxatives. Magnesium is a common topic in our sessions with clients. “It would be an emergency if you hadn’t had a bowel movement for a prolonged time, and you’re also experiencing major bloating or severe abdominal pain. Constipation can significantly decrease quality of life, causing abdominal discomfort, a loss of appetite, bloating, and, if not corrected, can even lead to serious Drinking 2 Yakults / day also will work for me. should not be used) in those with a fecal impaction as it could make the situation even worse. He has been taking a fiber supplement, Ducolax and dring alot of water. do not take more than directed unless advised by your doctor. • Measure a capful of MiraLAX in 8 ounces of liquid, half of a capful in 4 ounces, or a teaspoon of MiraLAX in 2 ounces. Try an omelet with fresh spinach and tomatoes. (PEG). Lack of energy. Just one dose of miralax, low fodmap and 40 oz of water a day. Increasing activity and exercise can also improve constipation. 5 million physician office visits annually. The answer to this question is yes, dogs can take Miralax as long as it is prescribed by a veterinarian. Constipation is a common problem in Parkinson's disease (PD), occurring in about 50–60% of patients and may occur even before the motor symptoms appear. Do not mix the MiraLAX earlier than the morning of the day. Feces that stay in the bowel too long before elimination become hard and dry. Constipation treatments for people with Crohn’s disease include making dietary. Chronic constipation is having two or more of these symptoms for three months. Passage of liquid fecal seepage. 1 out of 10 from a total of 253 ratings on Drugs. Among them, 223 (0. Learn More. g. 1. gas and bloating. mild allergic reaction †. She has been using it for four years now and very rarely complains anymore (if at all). Dizziness, lightheadedness, or fainting, especially when standing up suddenly from a sitting/lying position. Causes for ConstipationMiraLax, or polyethylene glycol, is an osmotic laxative, which means it draws water into the intestine and softens the stool. Both are considered natural fiber types, and both options can effectively ease constipation. This MiraLAX powder is quite effective at helping relieve occasional constipation. Predisposing factors include female sex, increasing age, low socioeconomic status, depression and a history of sexual abuse. Therefore this systematic review aims at providing a synopsis on clinical effects and safety of available treatment options for constipation in PD. Key takeaways: Miralax (polyethylene glycol 3350) is a laxative that helps relieve constipation. Frequency: once per day. Constipation can be distressing, uncomfortable, and even painful. The following fruit juices contain fiber, sorbitol, and water, and they can help relieve constipation. According to the site, the recommended daily dosage — if you’re 17 years or older — is 17 grams of Miralax powder dissolved in 4 to 8 ounces of a cold or warm beverage (like water, juice, or. 0 out of 10 from a total of 39 ratings on Drugs. 90 oz (Pack of 2) 59. One tablespoon. Of the total drug interactions, 214 are moderate, and 1 is minor. Fill the cap with MiraLAX up to the marked 17-gram line. Diabetes. There’s not a known interaction between Linzess and alcohol. Two 32-ounce bottles of Gatorade®. In her wise-mother gut, she wasn’t comfortable giving her toddler the full adult dose every day. Both parties verbalized understanding. , a study author from the Shenzhen Institute of Advanced Technology at the Chinese Academy of. People also take Metamucil or Citrucel to boost their fiber intake. 1. A feeling that not all stool has passed. Introduction. We've tried evertying, Prunes, Prune juice and OJ juice warmed up. Lowering medications that may have anticholinergic side effects may be necessary. Treat constipation with nutrition and movement as follows: Fiber intake: High-fiber foods are. Miralax works by causing the stool to retain water, thus softening it. Common hormone disorders that can cause constipation include: Chronic constipation is defined by Rome III criteria2: Presence of 2 or more of the following symptoms: Straining during ≥25% of defecations. Constipation is a worldwide health issue and its median prevalence was reported to be 14% in adults overall and 33. Depending on the cause and how someone chooses to treat it, constipation can last for a number of days or weeks. If a person decides to treat constipation. You know, that plugged up feeling you get in which you have to poop but you can’t. Prucalopride shouldn't be used by people with bowel obstructions or inflammatory bowel disease. 1. Mild side effects. 1. Both are considered natural fiber types, and both options can effectively ease constipation. Constipation can get worse over months and years. She was finally diagnosed with a chronic constipation problem and put on Miralax. This is not a complete list of side effects and others may occur. 5 to 1. The chronic symptoms of constipation reduce the quality of life of patients as well as social activities. MiraLax, an osmotic laxative, works by preventing the reabsorption of water, which causes water retention in the stool. Many of these food are naturally high in fiber, for more ideas, head over to Tasty High Fiber Foods for Kids. In this webinar, Michelle Spicka talks about the causes of pelvic floor. thirst. Your health providers can help you determine which additional laxatives to use “as-needed,” if a person hasn’t had a bowel movement for a few days. Common medication treatments for constipation include: bulk-forming laxatives, such as psyllium (Metamucil. Lack of regular exercise or physical movement. Frequency: once per day. Recent Australasian epidemiological studies of constipation report prevalences of 6–30%. Prior to starting the Miralax regimen, my daughter would suffer from daily stomach pain. Wall’s Constipation Cocktail (aka the Orange Poly-Fleet – sounds yummy): -Perform manual disempaction if indicated by stool in the rectal vault (the podcast has a great overview of an approach for this procedure) -Provide 1/2 bottle (8oz or ~250mL) of Magnesium Citrate orally in the ED. The maximum dose of Miralax per day for severe constipation is 34 grams once daily. 5% in those aged over 60 years [], with a higher susceptibility in females and individuals under a low socioeconomic status [1, 2]. Researchers suggest that the prevalence of chemotherapy-induced constipation is about 16% among people with. Miralax is prescribed for bowel preparation, acute constipation, and constipation. Then, mix it into a full. Gently Unblocks Your Gut. Lack of energy. The majority of those with PD experience two kinds of constipation. Free shipping, arrives in 3+ days. Constipation is one of the most common gastrointestinal disorders among patients with chronic kidney disease (CKD) partly because of their sedentary lifestyle, low fiber and fluid intake, concomitant medications (e. nausea. by helping the stool hold in more water, making it softer. Common side effects include GI symptoms, headache, fatigue, and dizziness. drowsiness. As it is not a fiber supplement, Miralax does not offer the same additional. They add volume to your stool to help push it through. Bulk up on fiber. One study noted that up to 80% of Parkinson’s patients suffer from constipation. Constipation is a common problem, and. Water and fruit juices are best for preventing constipation. gas and bloating. k. Moreover, it helps to maintain a healthy digestive system and promotes regularity. 31%) have parkinson's disease. “It is gentle enough that people will do it and aggressive enough that it will work,” Dr. MiraLAX is used to treat occasional. Miralax is an osmotic laxative that contains polyethylene glycol. Miralax helps pull water into the intestines, making it easier to pass a stool. We always recommend as much daily vigorous exercise as is. stomach pain. [25] A combination of 25 g of fiber and 1. Miralax is an osmotic laxative that contains polyethylene glycol. Ask which exercises are best for you. Everyone is different. However, drinking alcohol may cause constipation or diarrhea. If your symptoms aren’t severe or you have side. The poor ratings were generally due to cramping and diarrhea, not the taste. trouble breathing (generally goes away after a few hours) Most of these. Colace is used to treat and prevent constipation caused by hard stools. In comparison, Miralax is classified as an osmotic laxative and contains the active ingredient polyethylene glycol 3350 (PEG3350). This means that chronic constipation is a frequent problem and needs to be addressed when caring for patients with dementia. MiraLax (polyethylene glycol 3350) is a good substitute. Occasional irregularity is a fact of life, but you can minimize it with some basic steps. changes in your routine. 91 ounces (2. Surveys show that between 20% and 40% of. Table 1: Fiber Content of Some Common Foods Food Serving Size Grams of Fiber Per Serving Cheerios ™ 1/3 cup 3 All-Bran ® 1/3 cup 8. The trick with taking these laxatives is to take them regularly rather than when you need them. But, in 2017, some families. 00 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Medicines to Treat. Parkinson’s Disease: Combating Constipation (Part 2) Caffeine (a cup of coffee, for example). By [Su. Symptoms pretty much the same. Take a fiber supplement. Never exceed 3/4 teaspoon of Miralax for every 10 pounds of the dog’s body weight over a 24-hour period. Ignoring your body’s urges to pass stools. other medications, such as iron. Soluble fiber will dissolve into a. The best drugs for constipation aren't prescription ones. Difficulty swallowing, feelings of nausea and constipation are all common symptoms of Parkinson’s disease (PD). When Miralax is ingested, it stimulates the GI tract to retain water. Linaclotide (Linzess) and. For colonoscopy prep, the super high dose works great. Wael El-Nachef. Clinically, it is manifested by intolerance of oral intake and abdominal distention due to. A feeling that the rectum is blocked. It has a sugar and non-sugar option. Too much fiber without adequate water intake can also cause or worsen constipation. Some children who have been constipated for a long time begin to have accidents, soiling, and poop stains in the underwear. This food is commonly used to treat constipation, and it has a virtually no flavor and can be easily mixed with other foods. Gently tap or shake the cap in order to level out the powder and make sure it’s at the 17-gram line. on August 2, 2023. Key takeaways: Miralax (polyethylene glycol 3350) and Colace (docusate) are both over-the-counter medications for constipation. I had to move to extra strength senokat, ducolax, suppositories, and even fleet enemas. Insoluble fiber, which is primarily found in fruits and vegetables, makes stools softer and bulks them up. Updated on February 27, 2022. Learn about its side effects, cost, and more. Some, such as polyethylene glycol (Miralax), pull water into the colon to ease constipation. Stir the Miralax powder into water, juice, or Gatorade. Give your doctor a complete list of all your medications, including prescription drugs, over-the-counter medications, vitamins, dietary supplements, herbal products, and other laxatives. Some people may notice that they’re stooling. Laxatives shouldn’t be a long-term solution for. 41,771 satisfied customers. The 2009 ADAGIO study looked at whether rasagiline — a monoamine oxidase-B (MAO-B) inhibitor (these can minimize the enzyme MAO-B's breakdown of dopamine and ease movement symptoms) — could put the brakes on disease progression for people in early-stage Parkinson's. A federal judge has cleared the way for a MiraLAX lawsuit to proceed, involving claims that the laxative caused caused the development of acute kidney injury. Use the cap that comes on the medicine bottle. Spinal cord injury. Sensation of incomplete evacuation for ≥25% of defecations. Many people living with Parkinson’s have trouble with bladder overactivity that causes urinary urgency, frequency, and incontinence (unintentional leaking). Examples of osmotic laxatives include: Polyethylene glycol or PEG (Miralax, Glycolax) Magnesium citrate (Citroma) Magnesium hydroxide (Milk of Magnesia) Sorbitol. Parkinson’s disease is a common neurologic disorder that affects the substantia nigra of the brain by depleting dopamine-secreting neurons.